尹斌成
生物化工专业：博士生导师/硕士生导师
生物工程专业：博士生导师
生物学专业：硕士生导师
生物与医药专业（生物工程领域）：博士生导师/硕士生导师
尹斌成，教授，博士生导师，国家优秀青年科学基金获得者，现任职于williamhill官网生物反应器工程全国重点实验室。研究方向：生物分析及生物传感新技术的开发。主要致力于生物分析及生物传感原理的创新，核酸探针设计等分析化学与生命科学交叉领域的基础与应用研究，并推动其在生物基础研究、体外诊断和疾病治疗等领域的广泛应用。
研究内容包括：
1、智能核酸纳米器件构建与疾病诊疗应用
2、可编程RNA传感新技术开发与生物应用
3、高效能核酸探针的设计与合成
4、液体活检新技术开发
迄今，已在SCI期刊上发表研究论文110余篇，包括Nat. Commnun.，J. Am. Chem. Soc.，Angew. Chem. Int. Ed.，Proc. Natl. Acad. Sci. U.S.A.，Nucleic Acid Res.，Anal. Chem.，Chem. Sci.，Small，Biosens. Bioelectron.，Chem. Commun.等高水平专业期刊。应斯普林格出版社邀请，出版了一部英文专著。主持及参与了多项重要科研项目，包括国家自然科学基金项目（青年、面上、优秀青年及重点项目）、国家重点研发计划、上海市自然科学基金、上海市纳米专项等项目。曾获教育部自然科学奖二等奖、上海市技术发明奖二等奖、上海市曙光学者、明治乳业生命科学奖、石河子大学“绿洲学者”等荣誉和奖励。
发表论著：
1. Pin-Ru Chen, Pei-Pei Qin, Ya-Nan Wang, Peng-Fu Liu, Xin-Yue Zhang, Nan Deng, Tao Qian, Bang-Ce Ye*, and Bin-Cheng Yin*. De novo design of a compact transcript degrader by engineering Cas6-CBS system and substrate-specific toxins. Nature Communications, 16, 8446, 2025.
2. Pei-Pei Qin, Pin-Ru Chen, Liu Tan, Xiaohe Chu, Bang-Ce Ye, and Bin-Cheng Yin*. Programming ADAR-recruiting hairpin RNA sensor to detect endogenous molecules. Nucleic Acids Research 53 (1), gkae1146, 2025.
3. Hai-Yan Jia, Shu-Yu Yao, Ying-Fu Li, Bang-Ce Ye, Bin-Cheng Yin*. A Conformational Switch-Controlled RNA Sensor Based on Orthogonal dCas12a for RNA Imaging in Live Cells. Biosensors and Bioelectronics 273, 117185, 2025.
4. Yu-Ting Sun, Pei-Pei Qin, Bang-Ce Ye, and Bin-Cheng Yin*. Identification and Purification of Specific Cell Populations via ADAR-based Synthetic Genetic Circuits. ACS Synthetic Biology 2025.
5. Wen-Zhuo Sun, Xin Wang, Meng-Yu Fu, Le-Fan Liu, Ping Zhang, Bin-Cheng Yin, Weibing Liu, and Bang-Ce Ye. Metabolic Engineering of Yarrowia lipolytica for Enhanced De Novo Biosynthesis of Icaritin. ACS Synthetic Biology 14, 1142-1151, 2025.
6. Hai-Yan Jia, Xin-Yue Zhang, Bang-Ce Ye, Bin-Cheng Yin*. An Orthogonal CRISPR/dCas12a System for RNA Imaging in Live Cells. Analytical Chemistry 96 (15), 5913-5921, 2024.
7. Liu Tan, Bang-Ce Ye, Bin-Cheng Yin*. Research and application of engineered gRNA technology in CRISPR/Cas system. Chinese Journal of Biochemistry and Molecular Biology 40 (8), 1078-1092, 2024.
8. Wei Du, Shanshan Jiang, Shengxiang Yin, Rongjiang Wang, Chunling Zhang, Bin-Cheng Yin, Jialin Li, Li Li, Nan Qi, Ying Zhou, Bang-Ce Ye. The microbiota-dependent tryptophan metabolite alleviates high-fat diet-induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis. Proceedings of the National Academy of Sciences of the United States of America 121 (35), e2400385121, 2024
9. Li Zhao, Shi-Yu Zhou, Yu Fu, Jin-Long Shen, Bin-Cheng Yin, Di You*, Bang-Ce Ye*. A dual program for CRP-mediated regulation in bacterial alarmone (p)ppGpp. mBio. 15 (11), e0243024, 2024
10. Pei-Qiang Ma, Fu-Wen Huang, Ya-Qi Xie, Hong-Rui Li, Hua-Dong Li, Bang-Ce Ye, and Bin-Cheng Yin*. A Universal DNA-based Sensing Toolbox for Programming Cell Functions. Journal of the American Chemical Society 145 (51), 28224-28232, 2023.
11. Hua-Dong Li, Guan-Hua Fang, Bang-Ce Ye, and Bin-Cheng Yin*. RNase H-Driven crRNA Switch Circuits for Rapid and Sensitive Detection of Various Analytical Targets. Analytical Chemistry 95 (50), 18549-18556, 2023.
12. Jian Xiang, Bang-Ce Ye, and Bin-Cheng Yin*. Functionalized Exosomes Reprogram the Targeted Recognition Between Tumor Cells and Immune Cells. China Biotechnology 43(10), 1-9, 2023.
13. Hua-Dong Li, Pei-Qiang Ma, Jin-Yu Wang, Bin-Cheng Yin*, and Bang-Ce Ye*. A DNA Nanodevice-Based Platform with Diverse Capabilities. Small 2302301, 2023.
14. He-Hua Zhang, Jian Xiang, Bin-Cheng Yin*, and Bang-Ce Ye*. Overcoming multidrug resistance of cancer cells by base-editing-induced nonsense mutations. ACS Pharmacology & Translational Science 6 (5), 812-819, 2023.
15. Jin-Yu Wang, Hua-Dong Li, Pei-Qiang Ma, Ying Zhou, Bin-Cheng Yin*, and Bang-Ce Ye*. An miRISC-initiated DNA nanomachine for monitoring microRNA activity in living cells. Biosensors and Bioelectronics 220 (15), 114828, 2023.
16. Yu Fu, Yu-Qi Dong, Jin-Long Shen, Bin-Cheng Yin, Bang-Ce Ye, Di You. A meet-up of acetyl phosphate and c-di-GMP modulates BldD activity for development and antibiotic production. Nucleic Acids Research 51 (13), 6870-6882, 2023.
17. Pei-Qiang Ma, Tian-Xian Liu, Hua-Dong Li, Bin-Cheng Yin*, and Bang-Ce Ye*. Nano-Biohybrid DNA Engager That Reprograms the T-Cell Receptor. Journal of the American Chemical Society 144 (49), 22458-22469, 2022.
18. Peipei Qin, Pinru Chen, Nan Deng, Liu Tan, Bin-Cheng Yin*, and Bang-Ce Ye*. Switching the Activity of CRISPR/Cas12a Using an Allosteric Inhibitory Aptamer for Biosensing. Analytical Chemistry 94 (45), 15908-15914, 2022.
19. Ting Wang, Yan Wang, Pinru Chen, Bin-Cheng Yin*, and Bang-Ce Ye*. An Ultrasensitive, One-Pot RNA Detection Method Based on Rationally Engineered Cas9 Nickase-Assisted Isothermal Amplification Reaction. Analytical Chemistry, 94, 12461-12471, 2022.
20. Hai-Yan Jia, Hong-Li Zhao, Ting Wang, Pin-Ru Chen, Bin-Cheng Yin*, and Bang-Ce Ye. A Programmable and Sensitive CRISPR/Cas12a-based MicroRNA Detection Platform Combined with Hybridization Chain Reaction. Biosensors and Bioelectronics 211, 114382, 2022.
21. Pinru Chen, Luying Wang, Peipei Qin, Bin-Cheng Yin*, and Bang-Ce Ye*. An RNA-based catalytic hairpin assembly circuit coupled with CRISPR-Cas12a for one-step detection of microRNAs. Biosensors and Bioelectronics 207, 114152, 2022.
22. Li Zhao, Di You, Ting Wang, Zhen-Ping Zou, Bin-Cheng Yin*, Ying Zhou*, Bang-Ce Ye*. Acylation driven by intracellular metabolites in host cells inhibits Cas9 activity used for genome editing. PNAS Nexus 1, 1-8, 2022.
23. Shi-Fu Liang, Fang-Fang Zuo, Bin-Cheng Yin*, and Bang-Ce Ye*. Delivery of siRNA based on engineered exosomes for glioblastoma therapy by targeting STAT3. Biomaterials Science 10, 1582-1590, 2022.
24. Lu Wang, Meng-Li Cheng, Fang He, Jian Xiang, Bin-Cheng Yin*, Bang-Ce Ye. Clearance of Tumor Exosomes by Engineered Exosomes-Assisted Phagocytosis of Macrophages. China Biotechnology 42 (6), 1-11, 2022.
25. Yi-Lin Shen, Liu-Qing Zhang, Ying Yang, Bin-Cheng Yin, Bang-Ce Ye, Ying Zhou. Advances in the role and mechanism of lactic acid bacteria in treating obesity. Food Bioengineering 1, 101-115, 2022.
26. Meng-Li Chen, Fang He, Bin-Cheng Yin*, and Bang-Ce Ye*. Simultaneous imaging of cancer biomarkers in live cells based on DNA-engineered exosomes. Analyst 146, 1626-1632, 2021.
27. Pei-Qiang Ma, Qing Huang, Hua-Dong Li, Bin-Cheng Yin*, and Bang-Ce Ye*. Multimachine Communication Network That Mimics the Adaptive Immune Response. Journal of the American Chemical Society 142 (8), 3851-3861, 2020.
28. Cui-Fang Ning, Luying Wang, Ya-Fei Tian, Bin-Cheng Yin*, and Bang-Ce Ye. Multiple and sensitive SERS detection of cancer-related exosomes based on gold-silver bimetallic nano-trepangs. Analyst 145, 2795-2804, 2020.
29. Luying Wang, Xingying Shen, Ting Wang, Pinru Chen, Nan Qi, Bin-Cheng Yin*, and Bang-Ce Ye*. A lateral flow strip combined with Cas9 nickase-triggered amplification reaction for multiplex detection of food-borne pathogens. Biosensors and Bioelectronics 165, 112364, 2020.
30. Huan-Huan Sun, Fang He, Ze-Yu Ye, Bin-Cheng Yin*, and Bang-Ce Ye. A Cas12a-mediated cascade amplification method for microRNA detection. Analyst 145, 5547-5552, 2020.
31. He-Hua Zhang, Li-Dong Zhao, Ze-Yu Ye, Peng Zuo, Bin-Cheng Yin*, and Bang-Ce Ye*. A telomerase-responsive nanoprobe to integrate diagnosis and treatment in tumor cells. Talanta 215, 120898, 2020.
32. Qing Huang, Pei-Qiang Ma, Hua-Dong Li, Bin-Cheng Yin*, and Bang-Ce Ye*. Catalytic-Hairpin-Assembly-Assisted DNA Tetrahedron Nanoprobe for Intracellular MicroRNA Imaging. ACS Applied Bio Materials 3 (5): 2861-2866, 2020.
33. Li-Dong Zhao, Peng Zuo, Bin-Cheng Yin*, Chenglin Hong*, and Bang-Ce Ye*. A Cell Membrane-Anchored DNA Tetrahedral Sensor for Real-time Monitoring of Exosome Secretion. Acta Chim. Sinica 78, 1076-1081, 2020.
34. Wenjun Li, Chaoyun Ma, Yiju Song, Chenglin Hong, Xiuwen Qiao, Bin-Cheng Yin*, Sensitive Detection of Carcinoembryonic Antigen (CEA) by a Sandwich-type Electrochemical Immunosensor using MoF-Ce@HA/Ag-HRP-Ab2 as a Nanoprobe. Nanotechnology 31, 185605, 2020.
35. Wen-Ping Wei, Yanzhe Shang, Ping Zhang, Yong Liu, Di You, Bin-Cheng Yin, and Bang-Ce Ye*. Engineering prokaryotic transcriptional activator XylR as xylose-inducible biosensor for transcription activation in yeast. ACS Synthetic Biology 9 (5), 1022-1029, 2020.
36. Ting Wang, Yong Liu, Huan-Huan Sun, Bin-Cheng Yin*, and Bang-Ce Ye*. An RNA-Guided Cas9 Nickase-Based Method for Universal Isothermal DNA Amplification. Angewandte Chemie International Edition 58, 5382-5386, 2019.
37. Fang He, Ze-Yu Ye, Li-Dong Zhao, Bin-Cheng Yin*, and Bang-Ce Ye*. Probing exosome internalization pathways through confocal microscopy imaging. Chemical Communications 55, 14015-14018, 2019.
38. Mei-Ling Gao, Bin-Cheng Yin*, and Bang-Ce Ye*. Construction of a DNA-AuNP-based Satellite Network for Exosome Analysis. Analyst 144, 5996-6003, 2019.
39. Cui-Fang Ning, Ya-Fei Tian, Wen Zhou, Bin-Cheng Yin*, and Bang-Ce Ye*. Ultrasensitive SERS Detection of Specific Oligonucleotides based on Au@AgAg Bimetallic Nanorods. Analyst 144, 2929-2935, 2019.
40. Mei-Ling Gao, Fang He, Bin-Cheng Yin*, and Bang-Ce Ye. A Dual Signal Amplification Method for Exosome Detection based on DNA Dendrimer Self-assembly. Analyst 144, 1995-2002, 2019.
41. Di You, Miao-Miao Wang, Bin-Cheng Yin, Bang-Ce Ye*. Precursor supply for erythromycin biosynthesis: engineering of propionate assimilation pathway based on propionylation modification. ACS Synthetic Biology 8, 371-380, 2019.
42. Di You, Ying Xu, Bin-Cheng Yin, Bang-Ce Ye*. Nitrogen regulator GlnR controls redox sensing and lipids anabolism by directly activating the whiB3 in Mycobacterium smegmatis. Frontiers in Microbiology 10, 74, 2019.
43. Shengyan Chen, Wenping Wei, Bin-Cheng Yin, Yanbin Tong, Jianjiang Lu, Bang-Ce Ye. Development of a highly sensitive whole-cell biosensors for arsenite detection through engineered promoter modifications. ACS Synthetic Biology 8 (10), 2295-2302, 2019.
44. Yong Liu, Chong-Yang Ren, Wen-Ping Wei, Di You, Bin-Cheng Yin, and Bang-Ce Ye*. A CRISPR-Cas9 strategy for activating the Saccharopolyspora erythraea erythromycin biosynthetic gene cluster with knock-in bidirectional promoters. ACS Synthetic Biology 8 (5), 1134-1143, 2019.
45. Pei-Qiang Ma, Cheng-Pin Liang, He-Hua Zhang, Bin-Cheng Yin,* and Bang-Ce Ye. A Highly Integrated DNA Nanomachine Operating in Living Cells Powered by Endogenous Stimulus. Chemical Science 9, 3299-3304, 2018.
46. Fang He, Jing Wang, Bin-Cheng Yin,* and Bang-Ce Ye*. Quantification of Exosome Based on a Copper-Mediated Signal Amplification Strategy. Analytical Chemistry, 90 (13), 8072-8079, 2018.
47. Ya-Fei Tian, Cui-Fang Ning, Fang He, Bin-Cheng Yin*, and Bang-Ce Ye*. Highly sensitive detection of exosomes by SERS using gold nanostar@Raman reporter@nanoshell structures modified with a bivalent cholesterol-labeled DNA anchor. Analyst 143, 4915-4922, 2018.
48. Zhi Yuan Mao, Lu Ning Zhu, Jie Gao, Jia Jun Liu, Yin Hui Wei, Xin Yu Li, Bin-Cheng Yin, * and Jian Wang*. A CoOOH Nanoflake-based Light Scattering Probe for the Simple and Selective Detection of Uric Acid in Human Serum. Analytical Methods 10, 4951-4957, 2018.
49. Yin Hui Wei, Xin Yu Li, Jie Gao, Jia Jun Liu, Dan Yuan, Bin-Cheng Yin,* and Jian Wang*. Size-dependent Modulation of CoOOH Nanoflakes Light Scattering for Rapid and Selective Detection of Tetracycline in Milk. Journal of Analysis and Testing 2, 332-341, 2018.
50. Yun Lv, Dan Cheng, Dongdong Su, Mei Chen, Bin-Cheng Yin, Lin Yuan,* and Xiao-Bing Zhang. Visualization of Oxidative Injury in the Mouse Kidney using Selective Superoxide Anion Fluorescent Probes. Chemical Science 9, 7606-7613, 2018.
51. Cheng-Pin Liang, Pei-Qiang Ma, Hui Liu, Xinggang Guo, Bin-Cheng Yin,* and Bang-Ce Ye. Rational Engineering of Dynamic, Entropy-Driven DNA Nanomachine for Intracellular MicroRNA Imaging. Angewandte Chemie International Edition 56 (31), 9077-9081, 2017.
52. Fang He, Hui Liu, Xinggang Guo, Bin-Cheng Yin,* and Bang-Ce Ye. Direct Exosome Quantification via Bivalent-Cholesterol-Labeled DNA Anchor for Signal Amplification. Analytical Chemistry 89 (23), 12968-12975, 2017.
53. Wen Zhou, Ya-Fei Tian, Bin-Cheng Yin,* and Bang-Ce Ye*. Simultaneous Surface-Enhanced Raman Spectroscopy Detection of Multiplexed MicroRNA Biomarkers. Analytical Chemistry 89 (11), 6120-6128, 2017.
54. Jin-Liang Ma, Bin-Cheng Yin,* Xin Wu, and Bang-Ce Ye. Simple and Cost-Effective Glucose Detection based on Carbon Nanodots Supported on Silver Nanoparticles. Analytical Chemistry 89 (2), 1323-1328, 2017.
55. Wen Zhou, Bin-Cheng Yin,* and Bang-Ce Ye*. Highly Sensitive Surface-Enhanced Raman Scattering Detection of Hexavalent Chromium based on Hollow Sea Urchin-Like TiO2@Ag Nanoparticle Substrate. Biosensors and Bioelectronics 87, 187-194, 2017.
56. Hong-Ya Wang, Jin-Liang Ma, Bin-Cheng Yin,* and Bang-Ce Ye*. Nicotinamide Adenine Dinucleotide Detection based on Silver Nanoclusters Stabilized by a Dumbbell-Shaped DNA Template. Analyst 142, 1765-1771, 2017.
57. Ya-Fei Tian, Wen Zhou, Bin-Cheng Yin,* and Bang-Ce Ye. Highly Sensitive Surface-enhanced Raman Scattering Detection of Adenosine Triphosphate based on Core-satellite Nanoassemblies. Analytical Methods 9, 6038-6043, 2017.
58. Dan Cheng, Yue Pan, Bin-Cheng Yin, Lin Yuan*, Xiao-Bing Zhang. A New Fluorescent Probe with Ultralow Background Fluorescence for Imaging of Endogenous Cellular Selenol under Oxidative Stress. Chinese Chemical Letters 28 (10), 1987-1990, 2017.
59. Jin-Liang Ma, Bin-Cheng Yin,* Xin Wu, and Bang-Ce Ye*. Copper-Mediated DNA-Scaffolded Silver Nanocluster On-Off Switch for Detection of Pyrophosphate and Alkaline Phosphatase. Analytical Chemistry 88 (18), 9219-9225, 2016.
60. Ru-Dong Li, Bin-Cheng Yin,* and Bang-Ce Ye*. Ultrasensitive, Colorimetric Detection of MicroRNAs based on Isothermal Exponential Amplification Reaction-Assisted Gold Nanoparticle Amplification. Biosensors and Bioelectronics 86, 1011-1016, 2016.
61. Di You, Bin-Cheng Yin, Zhi-Hai Li, Ying Zhou, Wen-Bang Yu, Peng Zuo, and Bang-Ce Ye*. Sirtuin-dependent reversible lysine acetylation of glutamine synthetases reveals an autofeedback loop in nitrogen metabolism. Proceedings of the National Academy of Sciences of the United States of America 113 (24), 6653-6658, 2016.
62. Qian Wang, Bin-Cheng Yin,* and Bang-Ce Ye*. A Novel Polydopamine-based Chemiluminescence Resonance Energy Transfer Method for MicroRNA Detection Coupling Duplex-Specific Nuclease-Aided Target Recycling Strategy. Biosensors and Bioelectronics 80, 366-372, 2016.
63. Jin-Liang Ma, Bin-Cheng Yin,* and Bang-Ce Ye*. A Versatile Proximity-Dependent Probe based on Light-Up DNA-Scaffolded Silver Nanoclusters. Analyst 141, 1301-1306, 2016.
64. Ru-Dong Li, Qian Wang, Bin-Cheng Yin,* and Bang-Ce Ye*. Enzyme-free Detection of Sequence-Specific MicroRNAs based on Nanoparticle-Assisted Signal Amplification Strategy. Biosensors and Bioelectronics 77, 995-1000, 2016.
65. Le Ying, Nuli Xie, Yanjing Yang, Xiaohai Yang, Qifeng Zhou, Bin-Cheng Yin, Jin Huang,* and Kemin Wang*. A Cell-Surface-Anchored Ratiometric I-Motif Sensor for Extracellular pH Detection. Chemical Communications 52, 7818-7821, 2016.
66. Jin-Liang Ma, Bin-Cheng Yin,* and Bang-Ce Ye*. DNA Template-Regulated Intergrowth of Fluorescent Silver Nanocluster Emitter Pair. RSC Advances 5, 98467-98471, 2015.
67. Qian Wang, Ru-Dong Li, Bin-Cheng Yin,* and Bang-Ce Ye*. Colorimetric Detection for Specific MicroRNA Based on Duplex-Specific Nuclease-Assisted Nanoparticle Amplification. Analyst 140, 6306-6312, 2015.
68. Jin-Liang Ma, Bin-Cheng Yin,* and Bang-Ce Ye*. A Novel Linear Molecular Beacon based on DNA-Scaffolded Silver Nanocluster for DNA Detection via Exonuclease III-Assisted Cyclic Amplification. RSC Advances 5, 65437-65443, 2015.
69. Jin-Liang Ma, Bin-Cheng Yin,* Huynh-Nhu Le, and Bang-Ce Ye*. Label-Free Detection of Sequence-Specific DNA based on Fluorescent Silver Nanoclusters-Assisted Surface Plasmon Enhanced Energy Transfer. ACS Applied Materials & Interfaces 7 (23), 12856-12863, 2015.
70. Peng-Qiang Leng, Feng-Lan Zhao, Bin-Cheng Yin,* and Bang-Ce Ye*. A Novel, Colorimetric Method for Biogenic Amine Detection based on Arylalkylamine N-Acetyltransferase. Chemical Communications 51, 8712-8714, 2015.
71. Bin-Cheng Yin, Shan Wu, Jin-Liang Ma, and Bang-Ce Ye*. A Novel Molecular Beacon-based Method for Isothermal Detection of Sequence-Specific DNA via T7 RNA Polymerase-Aided Target Regeneration. Biosensors and Bioelectronics 68, 365-370, 2015.
72. Cui-Yuan Yu, Bin-Cheng Yin,* Shilong Wang, Zengguang Xu, and Bang-Ce Ye*. Improved Ligation-Mediated PCR Method Coupled with T7 RNA Polymerase for Sensitive DNA Detection. Analytical Chemistry 86, 7214-7218, 2014.
73. Bin-Cheng Yin,* Jin-Liang Ma, Huynh-Nhu Le, Shilong Wang, Zengguang Xu, and Bang-Ce Ye*. A New Mode to Light Up Adjacent DNA-Scaffolded Silver Probe Pair and Its Application for Specific DNA Detection. Chemical Communications 50 (100), 15991-15994, 2014.
74. Yuan-Chen He, Bin-Cheng Yin,* Lihua Jiang, and Bang-Ce Ye*. Rapid Detection of MicroRNA based on p19-Enhanced Fluorescence Polarization. Chemical Communications 50 (47): 6236-6239, 2014.
75. Xiaoyan Lin, Liang Cui, Yishun Huang, Ya Lin, Yi Xie, Zhi Zhu*, Bin-Cheng Yin, Xi Chen, and Chaoyong James Yang*. Carbon Nanoparticle-Protected Aptamers for Highly Sensitive and Selective Detection of Biomolecules based on Nuclease-Assisted Target Recycling Signal Amplification. Chemical Communications 50, 7646-7648, 2014.
76. Jin Huang, Yong He, Xiaohai Yang, Kemin Wang, Le Ying, Ke Quan, Yanjing Yang, and Bin-Cheng Yin. I-Motif-Based Nano-Flares for Sensing pH Changes in Live Cells. Chemical Communications 50, 15768-15771, 2014.
77. Bin-Cheng Yin, Yu-Qiang Liu, and Bang-Ce Ye*. Sensitive Detection of MicroRNA in Complex Biological Samples via Enzymatic Signal Amplification Using DNA Polymerase Coupled with Nicking Endonuclease. Analytical Chemistry 85 (23), 11487-11493, 2013.
78. Cui-Yuan Yu, Bin-Cheng Yin,* and Bang-Ce Ye*. A Universal Real-Time PCR Assay for Rapid MicroRNA Quantification via the Enhancement of Base-Stacking Hybridization. Chemical Communications 49 (74), 8247-8249, 2013.
79. Min Zhang, Yu-Qiang Liu, Cui-Yuan Yu, Bin-Cheng Yin,* and Bang-Ce Ye*. Multiplexed Detection of MicroRNAs by Tuning DNA-Scaffolded Silver Nanoclusters. Analyst 138 (17), 4812- 4817, 2013.
80. Xin-Ping Wang, Bin-Cheng Yin,* and Bang-Ce Ye*. A Novel Fluorescence Probe of dsDNA-Templated Copper Nanoclusters for Quantitative Detection of MicroRNAs. RSC Advances 3, 8633-8636, 2013.
81. Xin-Ping Wang, Bin-Cheng Yin,* Ping Wang, and Bang-Ce Ye*. Highly Sensitive Detection of MicroRNAs based on Isothermal Exponential Amplification-Assisted Generation of Catalytic G-Quadruplex DNAzyme. Biosensors and Bioelectronics 42, 131-135, 2013.
82. Min Zhang, Huynh-Nhu Le, Xiao-Qin Jiang, Bin-Cheng Yin, and Bang-Ce Ye*. Time-Resolved Probes Based on Guanine/Thymine-Rich DNA-Sensitized Luminescence of Terbium (III). Analytical Chemistry 85 (23), 11665-11674, 2013.
83. Bin-Cheng Yin, Yu-Qiang Liu, and Bang-Ce Ye*. One-step, Multiplexed Fluorescence Detection of microRNAs Based on Duplex-Specific Nuclease Signal Amplification. Journal of the American Chemical Society 134 (11), 5064-5067, 2012.
84. Bin-Cheng Yin, Mingxu You, Weihong Tan, Bang-Ce Ye*. Mercury(II) Ions Detection via Pyrene-Mediated Photolysis of Disulfide Bonds. Chemistry - A European Journal 18 (5), 1286-1289, 2012.
85. Bin-Cheng Yin, Bang-Ce Ye*, Hui Wang, Zhi Zhu, Weihong Tan*. Colorimetric Logic Gates based on Aptamer-Crosslinked Hydrogel. Chemical Communications 48, 1248-1250, 2012.
86. Bin-Cheng Yin, Yi-Meng Guan, and Bang-Ce Ye*. An Ultrasensitive Electrochemical DNA Sensor based on the ssDNA-assisted Cascade of Hybridization Reaction. Chemical Communications 48 (35), 4208-4210, 2012.
87. Yu-Qiang Liu, Min Zhang, Bin-Cheng Yin, and Bang-Ce Ye*. Attomolar Ultrasensitive MicroRNA Detection by DNA-Scaffolded Silver-Nanocluster Probe based on Isothermal Amplification. Analytical Chemistry 84 (12), 5165-5169, 2012.
88. Di Wu, Bin-Cheng Yin, and Bang-Ce Ye*. A Label-Free Electrochemical DNA Sensor based on Exonuclease III-Aided Target Recycling Strategy for Sequence-Specific Detection of Femtomolar DNA. Biosensors and Bioelectronics 28, 232-238, 2011.
89. Mingxu You, Yan Chen, Lu Peng, Da Han, Bin-Cheng Yin, Bang-Ce Ye, and Weihong Tan*. Engineering DNA Aptamers for Novel Analytical and Biomedical Applications. Chemical Science 2, 1003-1010, 2011.
90. Hui-Jie Tong, Na Jin, Bin-Cheng Yin, and Bang-Ce Ye*. A Novel Separation and Enrichment Method of 17β-Estradiol using Aptamer-Anchored Beads. Bioprocess and Biosystems Engineering 34, 189-195, 2011.
91. Min Zhang, Bin-Cheng Yin, Weihong Tan, and Bang-Ce Ye*. A Versatile Graphene-Based Fluorescence “On/Off” Switch for Multiplex Detection of Various Targets. Biosensors and Bioelectronics 26, 3260-3265, 2011.
92. Min Zhang, Bin-Cheng Yin, Xian-Fei Wang, and Bang-Ce Ye*. Interaction of Peptides with Graphene Oxide and Its Application for Real-Time Monitoring of Protease Activity. Chemical Communications 47, 2399-2401, 2011.
93. Bin-Cheng Yin, Min Zhang, Weihong Tan*, and Bang-Ce Ye*. Peptide-Functionalized Spherical Polyelectrolyte Nanobrushes for Real-Time Sensing of Protease Activity. ChemBioChem 11, 494-497, 2010.
94. Bin-Cheng Yin, Peng Zuo, Hao Huo, Xinhua Zhong, and Bang-Ce Ye*. DNAzyme-Self-Assembled Gold Nanoparticles for Determination of Metal Ions using Fluorescence Anisotropy Assay. Analytical Biochemistry 401, 47-52, 2010.
95. Bin-Cheng Yin, Di Wu, and Bang-Ce Ye*. Sensitive DNA-based Electrochemical Strategy for Trace Bleomycins Detection. Analytical Chemistry 82 (19), 8272-8277, 2010.
96. Bin-Cheng Yin, Bang-Ce Ye*, Hui Wang, Weihong Tan*, and Cong-Cong Xie. An Allosteric Dual-DNAzyme Unimolecular Probe for Colorimetric Detection of Copper(II). Journal of the American Chemical Society 131 (41), 14624-14625, 2009.
97. Bin-Cheng Yin, Xian-Fei Wang, and Ye Bang-Ce*. Multiplex Genotyping and Allele Frequency Estimation using Non-Gel Capillary Electrophoresis. Analytical Biochemistry 387, 221-229, 2009.
98. Peng Zuo, Bin-Cheng Yin, Bang-Ce Ye*. DNAzyme-based Microarray for Highly Sensitive Detection of Metal Ions. Biosensors and Bioelectronics 25, 935-939, 2009.
99. Sheng-Quan Jin, Bin-Cheng Yin, and Bang-Ce Ye*. A Multiplexed Bead-based Mesofluidic System for Foodborne Pathogen Bacteria Detection. Applied and Environmental Microbiology 75, 6647-6654, 2009.
100. Bang-Ce Ye*, Bin-Cheng Yin. Highly Sensitive Detection of Mercury (II) ion by Fluorescence Polarization via Gold Nanoparticle Enhancement. Angewandte Chemie International Edition 47, 8386-8389, 2008.
101. Bin-Cheng Yin, Honghua Li, and Bang-Ce Ye*. A Dual-Probe Hybridization Method for Reducing Variability in Single Nucleotide Polymorphism Analysis with Oligonucleotide Microarrays. Analytical Biochemistry 383, 270-278, 2008.
102. Bin-Cheng Yin, Honghua Li, and Bang-Ce Ye*. Microarray-based Estimation of SNP Allele-frequency in Pooled DNA using the Langmuir Kinetic Model. BMC Genomics 9, 605, 2008.
103. Bin-Cheng Yin, Fei Yue, and Bang-Ce Ye*. Construction of Microarrays for Genotyping of DQA using Unmodified 45-mer Oligonucleotide. Molecular Biotechnology 36, 142-150, 2007.
104. Bang-Ce Ye, Min Zhang, Bin-Cheng Yin. 英文专著《Nano-Bio Probe Design and Its Application for Biochemical Analysis》, ISBN 978-3-642-29542-3, 施普林格出版社，2012.
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