徐慧颖
生物学专业：博士生导师/硕士生导师
食品科学与工程专业：硕士生导师
生物与医药专业（生物工程领域）：硕士生导师
徐慧颖，副教授，英国威廉希尔官网博士生导师。2010年6月毕业于河南师范大学生命科学学院，获理学学士。2016年6月毕业于复旦大学化学系，获理学博士学位。随后进入英国威廉希尔官网从事师资博士后研究工作，合作导师叶邦策教授。2018年11月留校任教，先后主持国家自然科学基金面上和青年项目、上海市自然科学基金面上项目、中国博士后科学基金面上项目等国家或省部级项目，2024年入选williamhill官网青年英才培育计划（A类）。在Analytical Chemistry，Biosensors and Bioelectronics，Chemical Communications等本领域权威期刊上发表SCI论文20余篇。
主要研究方向：
(1) 微纳生物传感与疾病诊断
致力于开发基于微流控芯片技术的生物传感系统，实现临床样本中痕量疾病标志物（外泌体、蛋白质等）的高效分离与高灵敏检测，为疾病筛查与预后监测提供潜在工具。
(2) 仿生纳米递送与肿瘤治疗
专注于构建新型仿生纳米药物递送系统。通过基于外泌体的膜工程与生物合成技术，设计兼具靶向性和治疗功能的智能载体，为发展个性化的肿瘤基因治疗与免疫疗法提供新方案。
主持的科研项目或基金：
1. 国家自然科学基金面上项目（22374048，主持）
2. 国家自然科学基金青年项目（21705047，主持）
3. 上海市自然科学基金面上项目（22ZR1417800，主持）
4. 中国博士后科学基金面上资助（2017M621380，主持）
5. 中央高校基本科研业务费青年教师探索研究基金（222201814030，主持）
教学：
主讲《生物化学》课程
主讲《生物化学实验》课程
代表性论文（*通讯作者, #共同一作）：
1. Huiying Xu#, Yujing Zhang#, Lihua Shen, Shu Yu, Changqing Li, Xianfei Zeng*, Qin Liu*, and Bang-Ce Ye*. Sensitive detection of exosomal biomarkers via a drop-shaped porous microfluidic chip for potential diagnosis of Alzheimer’s disease. Analytical Chemistry, 2025, 97, 15282.
2. Hongfeng Lu#, Zhen Gu#, Yilin Zou, Hua Wang, Siyu Lu, Huifeng Wang, Bang-Ce Ye, and Huiying Xu*. Tri-recognition-mediated proximity ligation for quantitative analysis of exosomal protein-specific sialylation and application on a microfluidic platform. Analytical Chemistry, 2025, 97, 11883.
3. Lijun Xu, Siyu Lu, Hua Wang, Huiying Xu*, Bang-Ce Ye*. Dual-recognition triggered proximity ligation combined with a rolling circle amplification strategy for analysis of exosomal protein-specific glycosylation. Analytical Chemistry, 2023, 95, 15745.
4. Zhongwen Ma, Huiying Xu* and Bang-Ce Ye*. Recent progress in quantitative technologies for the analysis of cancer-related exosome proteins. Analyst, 2023, 148, 4954.
5. Huiying Xu, Bang-Ce Ye*. Integrated microfluidic platforms for tumor-derived exosome analysis. Trends in Analytical Chemistry, 2023, 158, 116860.
6. Lu Zheng, Hua Wang, Peng Zuo, Yueling Liu, Huiying Xu*, and Bang-Ce Ye*. Rapid on-chip isolation of cancer-associated exosomes and combined analysis of exosomes and exosomal proteins. Analytical Chemistry, 2022, 94, 7703.
7. Shifu Liang, Huiying Xu*, and Bang-Ce Ye*. Membrane-decorated exosomes for combination drug delivery and improved glioma therapy. Langmuir, 2022, 38, 299.
8. Huiying Xu, Chong Liao, Shifu Liang, Bang-Ce Ye*. A novel peptide-equipped exosomes platform for delivery of antisense oligonucleotides. ACS Applied Materials & Interfaces, 2021, 13, 10760.
9. Huiying Xu, Lu Zheng, Yu Zhou, Bang-Ce Ye*. An artificial enzyme cascade amplification strategy for highly sensitive and specific detection of breast cancer-derived exosomes, Analyst, 2021, 146, 5542.
10. Yu Zhou, Huiying Xu*, Hua Wang, and Bang-Ce Ye*. Detection of breast cancer-derived exosomes using the horseradish peroxidase-mimicking DNAzyme as an aptasensor. Analyst, 2020, 145, 107.
11. Huiying Xu, Bang-Ce Ye*. Advances in biosensing technologies for analysis of cancer-derived exosomes. Trends in Analytical Chemistry, 2020, 123, 115773.
12. Huiying Xu#, Chong Liao#, Peng Zuo, Ziwen Liu, and Bang-Ce Ye*. A magnetic-based microfluidic device for on-chip isolation and detection of tumor-derived exosomes. Analytical Chemistry, 2018, 90, 13451.
13. Huiying Xu, Chong Liao, Yujie Liu, Bang-Ce Ye*, and Baohong Liu*. Iron phthalocyanine decorated nitrogen-doped graphene biosensing platform for real-time detection of nitric oxide released from living cells. Analytical Chemistry, 2018, 90, 4438.
14. Huiying Xu, Fenghua Geng, Xiangyu Jiang, Congying Shao, Yongxiang Wang*, Kefeng Wang, Peng Qu, Maotian Xu, and Bang-Ce Ye*. Design of metal-ion-triggered assembly of label-free split G-quadruplex/duplex DNA for turn-on detection of Hg2+ in fetal calf serum. Sensors and Actuators B: Chemical, 2018, 255, 1024.
15. Huiying Xu, Jingjing Xiao, Ling Yan, Lina Zhu, and Baohong Liu*. An electrochemical sensor for selective detection of dopamine based on nickel tetrasulfonated phthalocyanine functionalized nitrogen-doped graphene nanocomposites. Journal of Electroanalytical Chemistry, 2016, 779, 92.
16. Huiying Xu, Fenghua Geng, Yongxiang Wang*, Maotian Xu, Xinhe Lai, Peng Qu, Yintang Zhang, and Baohong Liu*. A label-free fluorescent molecular switch for a DNA hybridization assay utilizing a G-quadruplex selective auramine. Chemical Communications, 2015, 51, 8622.
17. Huiying Xu, Jingjing Xiao, Baohong Liu*, Sophie Griveau, and Fethi Bedioui. Enhanced electrochemical sensing of thiols based on cobalt phthalocyanine immobilized on nitrogen-doped graphene. Biosensors and Bioelectronics, 2014, 66, 438.
联系方式：
邮箱：xuhuiying@ecust.edu.cn
地址：上海市徐汇区梅陇路130号 williamhill官网实验十八楼713